Stim2 anticorps (AA 471-656)

N° du produit ABIN7170837

L’anticorps Lapin Polyclonal anti-Stim2 a été validé pour WB, ELISA et IHC. Il convient pour détecter Stim2 dans des échantillons de Humain.

Aperçu rapide pour Stim2 anticorps (AA 471-656) (ABIN7170837)

Antigène: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stim2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Stim2 anticorps

Épitope: AA 471-656

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Stromal interaction molecule 2 protein (471-656AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Stim2

Antigène: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Autre désignation: STIM2

Sujet:

Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.

Aliases: FLJ39527 antibody, KIAA1482 antibody, STIM 2 antibody, STIM2 antibody, STIM2_HUMAN antibody, Stromal interaction molecule 2 antibody

UniProt: Q9P246

Pathways: TCR Signaling, BCR Signaling