SOCS2 anticorps (AA 1-198)

N° du produit ABIN7170996

Détail du produit anti-SOCS2 anticorps

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Épitope: AA 1-198

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS2 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SOCS2

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Autre désignation: SOCS2 (SOCS2 Produits)

Synonymes: anticorps CIS2, anticorps Cish2, anticorps SOCS-2, anticorps SSI-2, anticorps SSI2, anticorps STATI2, anticorps Cish1, anticorps Socs-1, anticorps Socs-2, anticorps si:dkey-202b22.1, anticorps socs2, anticorps cis2, anticorps ssi2, anticorps cish2, anticorps ssi-2, anticorps socs-2, anticorps stati2, anticorps 8030460M17, anticorps AI527257, anticorps AW108012, anticorps D130043N08Rik, anticorps JAB, anticorps hg, anticorps Cradd, anticorps Socs2, anticorps suppressor of cytokine signaling 2, anticorps suppressor of cytokine signaling 1, anticorps death domain-containing protein CRADD, anticorps suppressor of cytokine signaling 2 S homeolog, anticorps SOCS2, anticorps Socs1, anticorps Socs2, anticorps socs2, anticorps LOC100716104, anticorps socs2.S

Sujet:

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Aliases: CIS 2 antibody, CIS-2 antibody, CIS2 antibody, Cish 2 antibody, Cish2 antibody, Cytokine inducible SH2 protein 2 antibody, Cytokine-inducible SH2 protein 2 antibody, SOCS 2 antibody, SOCS-2 antibody, Socs2 antibody, SOCS2_HUMAN antibody, SSI 2 antibody, SSI-2 antibody, SSI2 antibody, STAT induced STAT inhibitor 2 antibody, STAT-induced STAT inhibitor 2 antibody, STATI 2 antibody, STATI2 antibody, Suppressor of cytokine signaling 2 antibody

UniProt: O14508

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus