SOCS4 anticorps (AA 1-270)

N° du produit ABIN7171004

Détail du produit anti-SOCS4 anticorps

Antigène: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Suppressor of cytokine signaling 4 protein (1-270AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SOCS4

Antigène: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Autre désignation: SOCS4 (SOCS4 Produits)

Synonymes: anticorps SOCS7, anticorps socs4, anticorps SOCS4, anticorps 3110032M18Rik, anticorps A730004F22Rik, anticorps AI427843, anticorps AU015727, anticorps AU015859, anticorps Socs7, anticorps SOCS6, anticorps socs7, anticorps socs4a, anticorps suppressor of cytokine signaling 4, anticorps SOCS4, anticorps socs4, anticorps Socs4

Sujet:

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.

Aliases: CIS4 antibody, Cish4 antibody, Cytokine inducible SH2 protein 4 antibody, DKFZp686J1568 antibody, HSPC060 antibody, SH2 domain containing SOCS box protein antibody, SOCS-4 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS4_HUMAN antibody, SOCS6 antibody, SOCS7 antibody, SSI4 antibody, STAI4 antibody, STAT induced STAT inhibitor 4 antibody, STAT4 antibody, STATI4 antibody, Suppressor of cytokine signaling 4 antibody, Suppressor of cytokine signaling 7 antibody

UniProt: Q8WXH5

Pathways: Signalistation JAK/STAT, EGFR Signaling Pathway