TIAM2 anticorps (AA 1500-1627)

N° du produit ABIN7171462

Détail du produit anti-TIAM2 anticorps

Antigène: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Épitope: AA 1500-1627

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAM2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 protein (1500-1627AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TIAM2

Antigène: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Autre désignation: TIAM2 (TIAM2 Produits)

Synonymes: anticorps STEF, anticorps TIAM-2, anticorps 3000002F19Rik, anticorps mKIAA2016, anticorps TIAM2, anticorps T-cell lymphoma invasion and metastasis 2, anticorps T cell lymphoma invasion and metastasis 2, anticorps T-cell lymphoma invasion and metastasis 2a, anticorps T-lymphoma invasion and metastasis-inducing protein 2, anticorps TIAM2, anticorps Tiam2, anticorps tiam2a, anticorps LOC100598161

Sujet:

Background: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA.

Aliases: FLJ41865 antibody, OTTHUMP00000017472 antibody, SIF and TIAM1 like exchange factor antibody, SIF and TIAM1-like exchange factor antibody, STEF antibody, T cell lymphoma invasion and metastasis 2 antibody, T lymphoma invasion and metastasis inducing protein 2 antibody, T-lymphoma invasion and metastasis-inducing protein 2 antibody, TIAM 2 antibody, TIAM-2 antibody, Tiam2 antibody, TIAM2_HUMAN antibody

UniProt: Q8IVF5

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha