TBC1D7 anticorps (AA 1-293) (HRP)
Aperçu rapide pour TBC1D7 anticorps (AA 1-293) (HRP) (ABIN7171661)
Antigène
Voir toutes TBC1D7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-293
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Fonction
- TBC1D7 Antibody, HRP conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human TBC1 domain family member 7 protein (1-293AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
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Autre désignation
- TBC1D7
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Sujet
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Background: Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Aliases: TBC1D7 antibody, TBC7 antibody, HSPC239 antibody, TBC1 domain family member 7 antibody, Cell migration-inducing protein 23 antibody
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UniProt
- Q9P0N9
Antigène
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