TRF1 anticorps (AA 260-439) (HRP)

N° du produit ABIN7171732

Cet anticorps anti-TRF1 est un anticorps Lapin Polyclonal détectant TRF1 dans ELISA. Adapté pour Humain.

Aperçu rapide pour TRF1 anticorps (AA 260-439) (HRP) (ABIN7171732)

Antigène: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRF1 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-TRF1 anticorps (HRP)

Épitope: AA 260-439

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Telomeric repeat-binding factor 1 protein (260-439AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRF1

Antigène: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Autre désignation: TERF1

Sujet:

Background: Binds the telomeric double-stranded 5\'-TTAGGG-3\' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5\'-TTAGGG-3\' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

Aliases: hTRF1 AS antibody, NIMA interacting protein 2 antibody, NIMA-interacting protein 2 antibody, PIN 2 antibody, PIN2 antibody, t TRF1 antibody, Telomeric protein Pin2 antibody, Telomeric protein Pin2/TRF1 antibody, Telomeric repeat binding factor (NIMA interacting) 1 antibody, Telomeric repeat binding factor 1 antibody, Telomeric repeat binding protein 1 antibody, Telomeric repeat-binding factor 1 antibody, TERF 1 antibody, Terf1 antibody, TERF1_HUMAN antibody, TRBF 1 antibody, TRBF1 antibody, TRF 1 antibody, TRF antibody, TTAGGG repeat binding factor 1 antibody, TTAGGG repeat-binding factor 1 antibody

UniProt: P54274

Pathways: Cycle Cellulaire, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity