TOLLIP anticorps (AA 86-163)

N° du produit ABIN7172257

Cet anticorps anti-TOLLIP est un anticorps Lapin Polyclonal détectant TOLLIP dans IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour TOLLIP anticorps (AA 86-163) (ABIN7172257)

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOLLIP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-TOLLIP anticorps

Épitope: AA 86-163

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Toll-interacting protein (86-163AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TOLLIP

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Autre désignation: TOLLIP

Sujet:

Background: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).

Aliases: Adapter protein antibody, FLJ33531 antibody, IL 1RAcPIP antibody, IL1RAcPIP antibody, TOLIP antibody, TOLIP_HUMAN antibody, Toll interacting protein antibody, Toll-interacting protein antibody, tollip antibody

UniProt: Q9H0E2