TLR1 anticorps (AA 25-580)

N° du produit ABIN7172261

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR1 dans IHC, ELISA et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour TLR1 anticorps (AA 25-580) (ABIN7172261)

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-TLR1 anticorps

Épitope: AA 25-580

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Toll-like receptor 1 protein (25-580AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TLR1

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Autre désignation: TLR1

Sujet:

Background: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Aliases: CD281 antibody, CD281 antigen antibody, KIAA0012 antibody, LPRS5 antibody, rsc786 antibody, TIL antibody, TIL. LPRS5 antibody, Tlr1 antibody, TLR1_HUMAN antibody, Toll (Drosophila) homolog antibody, Toll like receptor 1 antibody, Toll-like receptor 1 antibody, Toll/interleukin-1 receptor-like protein antibody

UniProt: Q15399

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades