TRIAP1 anticorps (AA 1-76)

N° du produit ABIN7172318

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIAP1 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour TRIAP1 anticorps (AA 1-76) (ABIN7172318)

Antigène: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIAP1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TRIAP1 anticorps

Épitope: AA 1-76

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human TP53-regulated inhibitor of apoptosis 1 protein (1-76AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRIAP1

Antigène: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Autre désignation: TRIAP1

Sujet:

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).

Aliases: p53-inducible cell-survival factor antibody, p53CSV antibody, Protein 15E1.1 antibody, TP53-regulated inhibitor of apoptosis 1 antibody, TRIA1_HUMAN antibody, Triap1 antibody, WF 1 antibody, WF1 antibody

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling