MIA3 anticorps (AA 1447-1626)

N° du produit ABIN7173309

Détail du produit anti-MIA3 anticorps

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Épitope: AA 1447-1626

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA3 est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Transport and Golgi organization protein 1 homolog protein (1447-1626AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MIA3

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Autre désignation: MIA3 (MIA3 Produits)

Synonymes: anticorps CG11098, anticorps Dmel\\CG11098, anticorps TANGO1, anticorps MIA3, anticorps 9130229H14Rik, anticorps A930039G15Rik, anticorps AU022327, anticorps B230399H06Rik, anticorps C80126, anticorps Gm1525, anticorps Tango, anticorps ARNT, anticorps D320, anticorps TANGO, anticorps UNQ6077, anticorps Transport and Golgi organization 1, anticorps MIA family member 3, ER export factor, anticorps melanoma inhibitory activity family, member 3, anticorps melanoma inhibitory activity protein 3, anticorps melanoma inhibitory activity family member 3, anticorps melanoma inhibitory activity 3, anticorps Tango1, anticorps MIA3, anticorps LOC100055507, anticorps mia3, anticorps Mia3

Sujet:

Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum (PubMed:27138255, PubMed:19269366). Required for correct assembly of COPII coat components at endoplasmic reticulum exit sites (ERES) and for the localization of SEC16A and membrane-bound ER-resident complexes consisting of CTAGE5 and PREB/SEC12 to ERES (PubMed:28442536).

Aliases: ARNT antibody, C219 reactive peptide antibody, C219-reactive peptide antibody, D320 antibody, Melanoma inhibitory activity family, member 3 antibody, Melanoma inhibitory activity protein 3 antibody, Mia3 antibody, MIA3_HUMAN antibody, RP11-378J18.4 antibody, TANGO antibody, Transport and Golgi organization protein 1 antibody, UNQ6077 antibody

UniProt: Q5JRA6