TRIB3 anticorps (AA 152-325) (Biotin)

N° du produit ABIN7173366

L’anticorps Lapin Polyclonal anti-TRIB3 a été validé pour ELISA. Il convient pour détecter TRIB3 dans des échantillons de Humain.

Aperçu rapide pour TRIB3 anticorps (AA 152-325) (Biotin) (ABIN7173366)

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB3 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-TRIB3 anticorps (Biotin)

Épitope: AA 152-325

Fonction: TRIB3 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Tribbles homolog 3 protein (152-325AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRIB3

Antigène: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Autre désignation: TRIB3

Sujet:

Background: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the \\\'Thr-308\\\' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.

Aliases: C20orf97 antibody, Neuronal cell death inducible putative kinase antibody, Neuronal cell death-inducible putative kinase antibody, NIPK antibody, p65 interacting inhibitor of NF-kappaB antibody, p65-interacting inhibitor of NF-kappa-B antibody, SINK antibody, SKIP 3 antibody, SKIP3 antibody, TRB 3 antibody, TRB-3 antibody, TRB3 antibody, TRIB 3 antibody, Trib3 antibody, TRIB3_HUMAN antibody, Tribbles homolog 3 antibody, Tribbles pseudokinase 3 antibody, Tribbles3 antibody

UniProt: Q96RU7

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha