TCHP anticorps (AA 1-498) (Biotin)

N° du produit ABIN7173374

Cet anticorps Lapin Polyclonal détecte spécifiquement TCHP dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour TCHP anticorps (AA 1-498) (Biotin) (ABIN7173374)

Antigène: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCHP est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-TCHP anticorps (Biotin)

Épitope: AA 1-498

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TCHP

Antigène: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Autre désignation: TCHP

Sujet:

Background: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).

Aliases: TCHP antibody, Trichoplein keratin filament-binding protein antibody, Protein TCHP antibody, Mitochondrial protein with oncostatic activity antibody, Mitostatin antibody, Tumor suppressor protein antibody

UniProt: Q9BT92