RAD51 anticorps (pThr309) (HRP)

N° du produit ABIN713120

Détail du produit anti-RAD51 anticorps (HRP)

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Épitope: pThr309

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Thr309 [GE(p-T)RI]

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RAD51

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Autre désignation: RAD51 (RAD51 Produits)

Synonymes: anticorps BRCC5, anticorps HRAD51, anticorps HsRad51, anticorps HsT16930, anticorps MRMV2, anticorps RAD51A, anticorps RECA, anticorps CRAD51, anticorps wu:fb38e12, anticorps zgc:77754, anticorps RGD1563603, anticorps ATRAD51, anticorps F22D1.20, anticorps F22D1_20, anticorps RAS associated with diabetes protein 51, anticorps AV304093, anticorps Rad51a, anticorps Reca, anticorps brcc5, anticorps rad51, anticorps rad51a, anticorps reca, anticorps xrad51, anticorps RAD51 recombinase, anticorps RAS associated with diabetes protein 51, anticorps RAD51 recombinase L homeolog, anticorps RAD51, anticorps rad51, anticorps Rad51, anticorps rad51.L

Sujet:

Synonyms: RAD51phospho T309, BRCA1/BRCA2 containing complex, subunit 5, BRCC 5, BRCC5, DNA repair protein RAD51 homolog 1, DNA repair protein rhp51, E coli RecA homolog, HGNC:9817, Homolog of E coli RecA, homolog of S cerevisiae RAD51, HRAD51, HsRad51, HsT16930, Rad 51, RAD51 homolog RecA homolog, E. coli S. cerevisiae, RAD51 homolog, RAD51 homolog S. cerevisiae, RAD51 S cerevisiae homolog, RAD51A, RECA, RecA homolog E. coli, RecA like protein, RecA, E. coli, homolog of, recombination protein A.

Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Transcript variants utilizing alternative polyA signals exist.

ID gène: 5888

Pathways: Réparation de l'ADN