TDP1 anticorps (AA 1-260)

N° du produit ABIN7174129

Détail du produit anti-TDP1 anticorps

Antigène: TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

Épitope: AA 1-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Tyrosyl-DNA phosphodiesterase 1 protein (1-260AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:2000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TDP1

Antigène: TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

Autre désignation: TDP1 (TDP1 Produits)

Synonymes: anticorps 2810481F14Rik, anticorps 4921509N21Rik, anticorps AI838772, anticorps AW493413, anticorps E430034L06Rik, anticorps MLZ-501, anticorps SCAN1, anticorps tdp1, anticorps MGC83708, anticorps TDP1, anticorps F8M21.60, anticorps F8M21_60, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA Phosphodiesterase (Tdp1), anticorps tyrosyl-DNA phosphodiesterase 1 L homeolog, anticorps tyrosyl-DNA phosphodiesterase-like protein, anticorps TDP1, anticorps Tc00.1047053511191.10, anticorps Tdp1, anticorps tdp1.L, anticorps tdp1, anticorps PTRG_11198, anticorps MCYG_02121, anticorps MGYG_03035

Sujet:

Background: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3\\\'-phosphodiester bond, giving rise to DNA with a free 3\\\' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3\\\'-phosphoglycolates on protruding 3\\\' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3\\\'exonuclease activity and can remove a single nucleoside from the 3\\\'end of DNA and RNA molecules with 3\\\'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3\\\'phosphate.

Aliases: AI838772 antibody, AW493413 antibody, FLJ11090 antibody, MGC104252 antibody, MGC112732 antibody, RP24-311F12.2 antibody, SCAN1 antibody, TDP1 antibody, TYDP antibody, TYDP1_HUMAN antibody, Tyr-DNA phosphodiesterase 1 antibody, Tyrosyl-DNA phosphodiesterase 1 antibody

UniProt: Q9NUW8