USP5 anticorps (AA 201-500)

N° du produit ABIN7174348

Cet anticorps anti-USP5 est un anticorps Lapin Polyclonal détectant USP5 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour USP5 anticorps (AA 201-500) (ABIN7174348)

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-USP5 anticorps

Épitope: AA 201-500

Fonction: USP5 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 5 protein (201-500AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur USP5

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Autre désignation: USP5

Sujet:

Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \\\'Lys-48\\\'-linked polyubiquitin disassembly. Binds linear and \\\'Lys-63\\\'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Aliases: Deubiquitinating enzyme 5 antibody, Isopeptidase T antibody, ISOT 1 antibody, ISOT antibody, Ubiquitin carboxyl-terminal hydrolase 5 antibody, Ubiquitin isopeptidase T antibody, Ubiquitin specific peptidase 5 (isopeptidase T) antibody, Ubiquitin specific peptidase 5 antibody, Ubiquitin specific processing protease 5 antibody, Ubiquitin specific protease 5 (isopeptidase T) antibody, Ubiquitin specific protease 5 (ubiquitin isopeptidase T) antibody, Ubiquitin thioesterase 5 antibody, Ubiquitin thiolesterase 5 antibody, Ubiquitin-specific-processing protease 5 antibody, UBP5_HUMAN antibody, Usp5 antibody

UniProt: P45974