RPS27A anticorps (AA 16-56)

N° du produit ABIN7174405

Détail du produit anti-RPS27A anticorps

Antigène: RPS27A (Ribosomal Protein S27a (RPS27A))

Épitope: AA 16-56

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS27A est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin-40S ribosomal protein S27a protein (16-56AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RPS27A

Antigène: RPS27A (Ribosomal Protein S27a (RPS27A))

Autre désignation: RPS27A (RPS27A Produits)

Synonymes: anticorps CEP80, anticorps S27A, anticorps UBA80, anticorps UBC, anticorps UBCEP1, anticorps UBCEP80, anticorps 0610006J14Rik, anticorps Uba52, anticorps Ubb, anticorps Ubc, anticorps CG5271, anticorps DUb80, anticorps Dmel\\CG5271, anticorps Dub80, anticorps UB3-D, anticorps Ubi-f80, anticorps Ubi-m, anticorps Ubiq, anticorps l(2)04820, anticorps l(2)31Ei, anticorps mfs(2)31, anticorps mfs(2)48, anticorps mfs48, anticorps Ubiz, anticorps hm:zeh0386, anticorps ik:tdsubc_1f2, anticorps tdsubc_1f2, anticorps xx:tdsubc_1f2, anticorps zgc:66168, anticorps rps27a, anticorps rps27a.L, anticorps ribosomal protein S27a, anticorps ribosomal protein S27A, anticorps Ribosomal protein S27A, anticorps ubiquitin-40S ribosomal protein S27a, anticorps ribosomal protein S27a S homeolog, anticorps RPS27A, anticorps Rps27a, anticorps RpS27A, anticorps rps27a, anticorps LOC105381543, anticorps rps27a.S

Sujet:

Background: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

Aliases: RPS27A antibody, UBA80 antibody, UBCEP1 antibody, Ubiquitin-40S ribosomal protein S27a antibody, Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin, 40S ribosomal protein S27a antibody, Small ribosomal subunit protein eS31)] antibody

UniProt: P62979

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation