UBE2K anticorps (AA 2-200) (Biotin)

N° du produit ABIN7174462

Cet anticorps anti-UBE2K est un anticorps Lapin Polyclonal détectant UBE2K dans ELISA. Adapté pour Humain.

Aperçu rapide pour UBE2K anticorps (AA 2-200) (Biotin) (ABIN7174462)

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2K est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-UBE2K anticorps (Biotin)

Épitope: AA 2-200

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin-conjugating enzyme E2 K protein (2-200AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBE2K

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Autre désignation: UBE2K

Sujet:

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of \'Lys-48\'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.

Aliases: E2 25K antibody, E2(25K) antibody, HIP-2 antibody, Huntingtin interacting protein 2 antibody, Huntingtin-interacting protein 2 antibody, HYPG antibody, LIG antibody, UBC1 antibody, UBE2K antibody, UBE2K_HUMAN antibody, Ubiquitin carrier protein antibody, Ubiquitin conjugating enzyme E2 25 kDa antibody, ubiquitin conjugating enzyme E2K antibody, ubiquitin conjugating enzyme E2K (UBC1 homolog, yeast) antibody, Ubiquitin protein ligase antibody, Ubiquitin-conjugating enzyme E2 K antibody, Ubiquitin-conjugating enzyme E2(25K) antibody, Ubiquitin-conjugating enzyme E2-25 kDa antibody, Ubiquitin-conjugating enzyme E2-25K antibody, Ubiquitin-protein ligase antibody

UniProt: P61086