ATG7 anticorps (AA 386-676) (HRP)

N° du produit ABIN7174541

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG7 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour ATG7 anticorps (AA 386-676) (HRP) (ABIN7174541)

Antigène: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG7 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-ATG7 anticorps (HRP)

Épitope: AA 386-676

Fonction: ATG7 Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Ubiquitin-like modifier-activating enzyme ATG7 protein (386-676AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ATG7

Antigène: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Autre désignation: ATG7

Sujet:

Background: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.

Aliases: 1810013K23Rik antibody, Apg 7 antibody, APG7 autophagy 7 like antibody, APG7 autophagy 7-like (S. cerevisiae) antibody, APG7 like antibody, APG7, S. cerevisiae, homolog of antibody, APG7-like antibody, APG7L antibody, ATG 7 antibody, ATG12-activating enzyme E1 ATG7 antibody, ATG7 antibody, ATG7 autophagy related 7 homolog (S. cerevisiae) antibody, ATG7 autophagy related 7 homolog antibody, ATG7_HUMAN antibody, Atg7l antibody, Autophagy 7, S. cerevisiae, homolog of antibody, Autophagy related protein 7 antibody, Autophagy-related 7 (yeast) antibody, Autophagy-related protein 7 antibody, DKFZp434N0735 antibody, GSA 7 antibody, GSA7 antibody, hAGP7 antibody, Ubiquitin activating enzyme E1 like protein antibody, Ubiquitin-activating enzyme E1-like protein antibody, Ubiquitin-like modifier-activating enzyme ATG7 antibody

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy