RAD23A anticorps (AA 2-201)

N° du produit ABIN7175170

Détail du produit anti-RAD23A anticorps

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Épitope: AA 2-201

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human UV excision repair protein RAD23 homolog A protein (2-201AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAD23A

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Autre désignation: RAD23A (RAD23A Produits)

Synonymes: anticorps rad23a, anticorps wu:fe11h06, anticorps zgc:92001, anticorps RAD23A, anticorps HHR23A, anticorps HR23A, anticorps 2310040P19Rik, anticorps AL024030, anticorps mHR23A, anticorps RAD23 homolog A, nucleotide excision repair protein a, anticorps RAD23 homolog A, nucleotide excision repair protein, anticorps rad23aa, anticorps RAD23A, anticorps Rad23a

Sujet:

Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to \\\'Lys-48\\\'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to \\\'Lys-63\\\'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.

Aliases: hHR 23A antibody, hHR23A antibody, HR23A antibody, MGC111083 antibody, RAD 23a antibody, RAD23 homolog A (S. cerevisiae) antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23A antibody, RD23A_HUMAN antibody, UV excision repair protein RAD23 antibody, UV excision repair protein RAD23 homolog A antibody

UniProt: P54725

Pathways: Réparation de l'ADN