VPS52 anticorps (AA 277-377)
Aperçu rapide pour VPS52 anticorps (AA 277-377) (ABIN7175328)
Antigène
Voir toutes VPS52 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 277-377
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: IHC:1:200-1:500,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))
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Autre désignation
- VPS52
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Sujet
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Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
Aliases: VPS52 antibody, SACM2LVacuolar protein sorting-associated protein 52 homolog antibody, SAC2 suppressor of actin mutations 2-like protein antibody
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UniProt
- Q8N1B4
Antigène
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