VPS52 anticorps (AA 277-377) (HRP)

N° du produit ABIN7175331

Détail du produit anti-VPS52 anticorps (HRP)

Antigène: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Épitope: AA 277-377

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS52 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur VPS52

Antigène: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Autre désignation: VPS52 (VPS52 Produits)

Synonymes: anticorps ARE1, anticorps RP5-1033B10, anticorps SAC2, anticorps SACM2L, anticorps dJ1033B10.5, anticorps Are1, anticorps Sacm2l, anticorps D130068D18, anticorps D430041K17Rik, anticorps fb94c11, anticorps sacm2l, anticorps wu:fb94c11, anticorps VPS52, GARP complex subunit, anticorps VPS52 GARP complex subunit, anticorps vacuolar protein sorting 52 homolog (S. cerevisiae), anticorps VPS52, anticorps Vps52, anticorps vps52

Sujet:

Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Aliases: VPS52 antibody, SACM2LVacuolar protein sorting-associated protein 52 homolog antibody, SAC2 suppressor of actin mutations 2-like protein antibody

UniProt: Q8N1B4