WAC anticorps (AA 10-102) (FITC)
Aperçu rapide pour WAC anticorps (AA 10-102) (FITC) (ABIN7175869)
Antigène
Voir toutes WAC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 10-102
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
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Autre désignation
- WAC
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Sujet
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Background: Acts as a linker between gene transcription and histone H2B monoubiquitination at \\\'Lys-120\\\' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.
Aliases: 1110067P07Rik antibody, BA48B24 antibody, BA48B24.1 antibody, BM 016 antibody, FLJ31290 antibody, KIAA1844 antibody, MGC10753 antibody, OTTHUMP00000019380 antibody, OTTHUMP00000019382 antibody, PRO1741 antibody, wac antibody, WAC_HUMAN antibody, WW domain containing adapter protein with coiled coil antibody, WW domain containing adaptor with coiled coil antibody, WW domain-containing adapter protein with coiled-coil antibody, Wwp4 antibody
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UniProt
- Q9BTA9
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Pathways
- Chromatin Binding
Antigène
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