TRIM27 anticorps (AA 214-513)

N° du produit ABIN7176599

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIM27 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour TRIM27 anticorps (AA 214-513) (ABIN7176599)

Antigène: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM27 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TRIM27 anticorps

Épitope: AA 214-513

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Zinc finger protein RFP protein (214-513AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRIM27

Antigène: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Autre désignation: TRIM27

Sujet:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of \\\'Lys-48\\\'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of \\\'Lys-63\\\'-linked polyubiquitin chains at \\\'Lys-220\\\' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.

Aliases: AW538890 antibody, DAAP-182E11.3 antibody, MGC189472 antibody, OTTHUMP00000029314 antibody, Ret finger protein antibody, RFP antibody, RFP transforming protein antibody, Rfp1 antibody, RING finger protein 76 antibody, RNF76 antibody, TRI27_HUMAN antibody, TRIM 27 antibody, Trim27 antibody, Tripartite motif containing 27 antibody, Tripartite motif containing protein 27 antibody, Tripartite motif protein TRIM27 antibody, Tripartite motif-containing protein 27 antibody, Zinc finger protein RFP antibody

UniProt: P14373