KEAP1 anticorps (AA 1-624) (FITC)

N° du produit ABIN7177371

L’anticorps Lapin Polyclonal anti-KEAP1 a été validé pour . Il convient pour détecter KEAP1 dans des échantillons de Souris.

Aperçu rapide pour KEAP1 anticorps (AA 1-624) (FITC) (ABIN7177371)

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KEAP1 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-KEAP1 anticorps (FITC)

Épitope: AA 1-624

Fonction: Keap1 Antibody, FITC conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KEAP1

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Autre désignation: Keap1

Sujet:

Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).

Aliases: Keap1 antibody, Inrf2 antibody, Kiaa0132Kelch-like ECH-associated protein 1 antibody, Cytosolic inhibitor of Nrf2 antibody, INrf2 antibody

UniProt: Q9Z2X8

Pathways: Maintenance of Protein Location