Perforin 1 anticorps (AA 21-554)

N° du produit ABIN7177734

L’anticorps Lapin Polyclonal anti-Perforin 1 a été validé pour WB, ELISA et IF. Il convient pour détecter Perforin 1 dans des échantillons de Souris.

Aperçu rapide pour Perforin 1 anticorps (AA 21-554) (ABIN7177734)

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Perforin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Perforin 1 anticorps

Épitope: AA 21-554

Fonction: Prf1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Mouse Perforin-1 protein (21-554AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Perforin 1

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Autre désignation: Prf1

Sujet:

Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Aliases: Prf1 antibody, Pfp antibody, Perforin-1 antibody, P1 antibody, Cytolysin antibody, Lymphocyte pore-forming protein antibody

UniProt: P10820

Pathways: Apoptose, Caspase Cascade in Apoptosis