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PRNP anticorps (AA 29-231) (HRP)

Cet anticorps Lapin Polyclonal détecte spécifiquement PRNP dans ELISA. Il présente une réactivité envers Rat.
N° du produit ABIN7178936

Aperçu rapide pour PRNP anticorps (AA 29-231) (HRP) (ABIN7178936)

Antigène

Voir toutes PRNP Anticorps
PRNP (Prion Protein (PRNP))

Reactivité

  • 90
  • 33
  • 30
  • 13
  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Rat

Hôte

  • 83
  • 20
  • 2
  • 1
  • 1
Lapin

Clonalité

  • 74
  • 33
Polyclonal

Conjugué

  • 49
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp PRNP est conjugé à/à la HRP

Application

  • 55
  • 32
  • 27
  • 26
  • 19
  • 13
  • 9
  • 8
  • 7
  • 7
  • 6
  • 3
  • 1
  • 1
ELISA
  • Épitope

    • 15
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-231

     Réactivité croisée

    Rat

    Purification

    >95%, Protein G purified

    Immunogène

    Recombinant Rat Major prion protein (29-231AA)

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène

    PRNP (Prion Protein (PRNP))

    Autre désignation

    Prnp

    Sujet

    Background: Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.

    Aliases: Prnp antibody, Prn antibody, Prp antibody, Major prion protein antibody, PrP antibody, CD antigen CD230 antibody

    UniProt

    P13852

    Pathways

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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