SRI anticorps (AA 32-116) (Biotin)
Aperçu rapide pour SRI anticorps (AA 32-116) (Biotin) (ABIN7179480)
Antigène
Voir toutes SRI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 32-116
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Réactivité croisée
- Staphylococcus aureus
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)
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Isotype
- IgG
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anti-Sorcin (SRI) (AA 1-198) antibody
SRI Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1E12 unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Sorcin (SRI) antibodyKO Validated SRI Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Sorcin (SRI) (AA 29-169) antibodySRI Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Sorcin (SRI) (C-Term) antibodySRI Reactivité: Humain, Rat, Cheval, Chien, Boeuf (Vache), Mouton, Singe, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-Sorcin (SRI) (AA 96-145) antibodySRI Reactivité: Humain, Lapin, Singe WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SRI (Sorcin (SRI))
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Autre désignation
- scn
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Sujet
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Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody
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UniProt
- Q99SU9
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Pathways
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Antigène
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