SRI anticorps (AA 32-116) (FITC)

N° du produit ABIN7179481

Cet anticorps anti-SRI est un anticorps Lapin Polyclonal détectant SRI dans . Adapté pour Staphylococcus aureus.

Aperçu rapide pour SRI anticorps (AA 32-116) (FITC) (ABIN7179481)

Antigène: SRI (Sorcin (SRI))

Reactivité: Staphylococcus aureus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRI est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-SRI anticorps (FITC)

Épitope: AA 32-116

Réactivité croisée: Staphylococcus aureus

Purification: >95%, Protein G purified

Immunogène: Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SRI

Antigène: SRI (Sorcin (SRI))

Autre désignation: scn

Sujet:

Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.

Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody

UniProt: Q99SU9

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity