MBNL3 anticorps (AA 251-354)

N° du produit ABIN713756

Détail du produit anti-MBNL3 anticorps

Antigène: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Épitope: AA 251-354

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MBNL3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MBNL3

Antigène: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Autre désignation: MBNL3 (MBNL3 Produits)

Synonymes: anticorps A530038J18Rik, anticorps AI661274, anticorps CHCR, anticorps E430034C16Rik, anticorps MBLX, anticorps MBLX39, anticorps MBXL, anticorps mbxl, anticorps RGD1565834, anticorps muscleblind like splicing regulator 3, anticorps muscleblind like splicing factor 3, anticorps Muscleblind-like protein 3-like, anticorps muscleblind-like splicing regulator 3, anticorps MBNL3, anticorps Mbnl3, anticorps mbnl3

Sujet:

Synonyms: MBLX, CHCR, Cys3His CCG1 required protein, MBLX39, MBNL 3, MBXL, Muscleblind like protein 3, Muscleblind like X linked protein, Protein HCHCR, MBNL3_HUMAN.

Background: MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies.

ID gène: 55796

UniProt: Q9NUK0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development