KDM4B anticorps (C-Term)

N° du produit ABIN7180190

Cet anticorps Lapin Polyclonal détecte spécifiquement KDM4B dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour KDM4B anticorps (C-Term) (ABIN7180190)

Antigène: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-KDM4B anticorps

Épitope: C-Term

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human JHD3B.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KDM4B

Antigène: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Autre désignation: KDM4B

Sujet:

Background: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Nagase T., DNA Res. 5:355-364(1998).
Nakajima D., DNA Res. 9:99-106(2002).
Grimwood J., Nature 428:529-535(2004).

Aliases: JHDM3B antibody, JmjC domain-containing histone demethylation protein 3B antibody, JMJD2B antibody, Jumonji domain containing 2B antibody, Jumonji domain containing protein 2B antibody, Jumonji domain-containing protein 2B antibody, Kdm4b antibody, KDM4B_HUMAN antibody, KIAA0876 antibody, Lysine (K) specific demethylase 4B antibody, Lysine demethylase 4B antibody, Lysine-specific demethylase 4B antibody, TDRD14B antibody, Tudor domain containing 14B antibody

UniProt: O94953

Pathways: L'effet Warburg