UBA2 anticorps (C-Term)

N° du produit ABIN7180278

Détail du produit anti-UBA2 anticorps

Antigène: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human Uba2.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBA2

Antigène: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Autre désignation: UBA2 (UBA2 Produits)

Synonymes: anticorps ATSAE2, anticorps EMB2764, anticorps EMBRYO DEFECTIVE 2764, anticorps F3K23.23, anticorps F3K23_23, anticorps SUMO-ACTIVATING ENZYME 2, anticorps SUMO-activating enzyme 2, anticorps ARX, anticorps SAE2, anticorps AA986091, anticorps Arx, anticorps Sae2, anticorps UBA1, anticorps Ubl1a2, anticorps Uble1b, anticorps sae2, anticorps sae2-B, anticorps uba2-a, anticorps uba2-b, anticorps uble1b-B, anticorps sae2b, anticorps uble1b, anticorps wu:fi17g06, anticorps zgc:66354, anticorps SUMO1 activating enzyme subunit 2, anticorps SUMO-activating enzyme 2, anticorps ubiquitin like modifier activating enzyme 2, anticorps ubiquitin-like modifier activating enzyme 2, anticorps ubiquitin like modifier activating enzyme 2 L homeolog, anticorps MICPUN_63834, anticorps MICPUCDRAFT_36729, anticorps SAE2, anticorps UBA2, anticorps Uba2, anticorps uba2.L, anticorps uba2

Sujet:

Background: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002, 22: 4346 - 4357.
Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003, 278: 36621 - 36627.
R. Jrgen Dohmen, J. Biol. Chem., Jul 1995, 270: 18099.
Yoshiaki Azuma, FASEB J, Jun 2001, 10.1096.

Aliases: Anthracycline associated resistance ARX antibody, Anthracycline-associated resistance ARX antibody, ARX antibody, FLJ13058 antibody, HRIHFB2115 antibody, SAE 2 antibody, SAE2 antibody, SAE2_HUMAN antibody, SUMO 1 activating enzyme subunit 2 antibody, SUMO activating enzyme subunit 2 antibody, SUMO-activating enzyme subunit 2 antibody, UBA2 antibody, UBA2 ubiquitin activating enzyme E1 homolog antibody, Ubiquitin like 1 activating enzyme E1B antibody, Ubiquitin like modifier activating enzyme 2 antibody, Ubiquitin-like 1-activating enzyme E1B antibody, UBLE1B antibody

UniProt: Q9UBT2