S100A1 anticorps
Aperçu rapide pour S100A1 anticorps (ABIN7182653)
Antigène
Voir toutes S100A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- S100A1 Antibody
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Réactivité croisée
- Souris, Rat
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from Human S100 A1.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- S100A1 (S100 Calcium Binding Protein A1 (S100A1))
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Autre désignation
- S100A1
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Sujet
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Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Patrick Most, J. Biol. Chem., Nov 2003, 278: 48404 - 48412.
Miki Okada, J. Biol. Chem., Feb 2004, 279: 4221 - 4233.
Melanie Boerries, Mol. Cell. Biol., Jun 2007, 27: 4365 - 4373.
Patrick Most, J. Clin. Invest., Dec 2004, 114: 1550 - 1563.Aliases: Bpb antibody, NEF antibody, Protein S100-A1 antibody, S-100 protein alpha chain antibody, S-100 protein subunit alpha antibody, S100 alpha antibody, S100 beta antibody, S100 calcium binding protein A1 antibody, S100 calcium binding protein B antibody, S100 calcium-binding protein A1 antibody, S100 protein alpha polypeptide antibody, S100A antibody, s100a1 antibody, S100B antibody, S100beta antibody, S10A1_HUMAN antibody
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UniProt
- P23297
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Pathways
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
Antigène
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