MBTPS2 anticorps

N° du produit ABIN7183789

Détail du produit anti-MBTPS2 anticorps

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBTPS2 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human MBTPS2.

Isotype: IgG

Information d'application

Indications d'application: IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MBTPS2

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Autre désignation: MBTPS2 (MBTPS2 Produits)

Synonymes: anticorps BRESEK, anticorps IFAP, anticorps KFSDX, anticorps S2P, anticorps 9630032G22Rik, anticorps AI662535, anticorps LRRGT00063, anticorps membrane bound transcription factor peptidase, site 2, anticorps membrane-bound transcription factor peptidase, site 2, anticorps MBTPS2, anticorps Mbtps2

Sujet:

Background: Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.

Rawson R.B., Mol. Cell 1:47-57(1997).
Ye J., Proc. Natl. Acad. Sci. U.S.A. 97:5123-5128(2000).

Aliases: BRESEK antibody, Endopeptidase S2P antibody, IFAP antibody, KFSDX antibody, MBTP2_HUMAN antibody, MBTPS2 antibody, Membrane bound transcription factor site 2 protease antibody, membrane-bound transcription factor peptidase, site 2 antibody, membrane-bound transcription factor protease, site 2 antibody, Membrane-bound transcription factor site-2 protease antibody, S2P antibody, S2P endopeptidase antibody, Site 2 protease antibody, SREBPs intramembrane protease antibody, Sterol regulatory element-binding proteins intramembrane protease antibody

UniProt: O43462

Pathways: ER-Nucleus Signaling