ARHGAP17 anticorps

N° du produit ABIN7184394

L’anticorps Lapin Polyclonal anti-ARHGAP17 a été validé pour WB et ELISA. Il convient pour détecter ARHGAP17 dans des échantillons de Humain.

Aperçu rapide pour ARHGAP17 anticorps (ABIN7184394)

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP17 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ARHGAP17 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of HumanRHG17.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARHGAP17

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Autre désignation: ARHGAP17

Sujet:

Background: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Richnau N., J. Biol. Chem. 276:35060-35070(2001).
Ota T., Nat. Genet. 36:40-45(2004).
The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.

Aliases: ARHGAP17 antibody, RICH1 antibody, MSTP066 antibody, MSTP110 antibody, Rho GTPase-activating protein 17 antibody, Rho-type GTPase-activating protein 17 antibody, RhoGAP interacting with CIP4 homologs protein 1 antibody, RICH-1 antibody

UniProt: Q68EM7