Topoisomerase II alpha anticorps (N-Term)

N° du produit ABIN7184512

Cet anticorps anti-Topoisomerase II alpha est un anticorps Lapin Polyclonal détectant Topoisomerase II alpha dans WB, IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour Topoisomerase II alpha anticorps (N-Term) (ABIN7184512)

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Topoisomerase II alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Topoisomerase II alpha anticorps

Épitope: N-Term

Fonction: TOP2A Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human TOP2A.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Topoisomerase II alpha

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Autre désignation: TOP2A

Sujet:

Background: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.

Tsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).
Wasserman R.A., Cancer Res. 53:3591-3596(1993).
Lang A.J., Gene 221:255-266(1998).

Aliases: alpha isozyme antibody, ATP hydrolyzing DNA topoisomerase II alfa antibody, DNA gyrase antibody, DNA topoisomerase (ATP hydrolyzing) antibody, DNA topoisomerase 2 alpha antibody, DNA topoisomerase 2-alpha antibody, DNA topoisomerase II 170 kD antibody, DNA topoisomerase II alpha isozyme antibody, DNA topoisomerase II antibody, DNA Topoisomerase2 antibody, TOP 2A antibody, TOP2 antibody, TOP2A antibody, TOP2A_HUMAN antibody, Topoisomerase DNA II alpha 170 kDa antibody, TP2A antibody

UniProt: P11388

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases