SIGLEC8 anticorps
Aperçu rapide pour SIGLEC8 anticorps (ABIN7192372)
Antigène
Voir toutes SIGLEC8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SIGLEC8 Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of Human SIGLEC8
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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Autre désignation
- SIGLEC8
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Sujet
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Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).
Aliases: CD329 antigen antibody, CDw329 antibody, SAF 2 antibody, SAF-2 antibody, SAF2 antibody, Sialic acid binding Ig like lectin 8 antibody, Sialic acid-binding Ig-like lectin 8 antibody, Sialoadhesin family member 2 antibody, SIGL8_HUMAN antibody, Siglec 8 antibody, Siglec-8 antibody, SIGLEC8 antibody, SIGLEC8L antibody
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UniProt
- Q9NYZ4
Antigène
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