IL21 Receptor anticorps (AA 20-232)

N° du produit ABIN7193230

Détail du produit anti-IL21 Receptor anticorps

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Épitope: AA 20-232

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL21 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CD360 (AA: extra 20-232) expressed in E. coli.

Clone: 8H10G4D12

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur IL21 Receptor

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Autre désignation: CD360 (IL21R Produits)

Synonymes: anticorps IL21R, anticorps il-21ra.a, anticorps CD360, anticorps NILR, anticorps interleukin 21 receptor, anticorps interleukin 21 receptor, tandem duplicate 1, anticorps IL21R, anticorps il21r.1, anticorps Il21r

Sujet:

Description: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Aliases: IL21R, NILR, IMD56

Poids moléculaire: 59.1 kDa

ID gène: 50615

Pathways: Signalistation JAK/STAT