ITGA4 anticorps (AA 833-977)
Aperçu rapide pour ITGA4 anticorps (AA 833-977) (ABIN7193242)
Antigène
Voir toutes ITGA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 833-977
-
Fonction
- CD49D Antibody
-
Purification
- Purified antibody
-
Immunogène
- Purified recombinant fragment of human CD49D (AA: 833-977) expressed in E. Coli.
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- ITGA4 (Integrin alpha 4 (ITGA4))
-
Autre désignation
- CD49D
-
Sujet
-
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
-
Poids moléculaire
- 114.9 kDa
-
ID gène
- 3676
-
UniProt
- P13612
-
Pathways
- Integrin Complex
Antigène
-