LRP6 anticorps (AA 1198-1370)

N° du produit ABIN7193277

Cet anticorps anti-LRP6 est un anticorps Souris Monoclonal détectant LRP6 dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour LRP6 anticorps (AA 1198-1370) (ABIN7193277)

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LRP6 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 1A3F5

Détail du produit anti-LRP6 anticorps

Épitope: AA 1198-1370

Fonction: LRP6 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human LRP6 (AA: 1198-1370) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur LRP6

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6

Sujet:

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

Poids moléculaire: 180 kDa

UniProt: O75581

Pathways: Signalisation WNT, Tube Formation