CD27 anticorps (AA 20-144)

N° du produit ABIN7193332

Cet anticorps Souris Monoclonal détecte spécifiquement CD27 dans FACS et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CD27 anticorps (AA 20-144) (ABIN7193332)

Antigène: CD27 (CD27 Molecule (CD27))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD27 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: 3B6D3

Détail du produit anti-CD27 anticorps

Épitope: AA 20-144

Fonction: CD27 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD27 (AA: 20-144) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CD27

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: CD27

Sujet:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Poids moléculaire: 29.1 kDa

ID gène: 939

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints