IL17RA anticorps (AA 33-320)
Aperçu rapide pour IL17RA anticorps (AA 33-320) (ABIN7193333)
Antigène
Voir toutes IL17RA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 33-320
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Fonction
- CD217 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CD217 (AA: 33-320) expressed in E. Coli.
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Isotype
- IgG2b
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IL17RA (Interleukin 17 Receptor A (IL17RA))
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Autre désignation
- CD217
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Sujet
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Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Poids moléculaire
- 96.1 kDa
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ID gène
- 23765
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UniProt
- Q96F46
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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