TLR9 anticorps (AA 26-193)

N° du produit ABIN7193346

Cet anticorps anti-TLR9 est un anticorps Souris Monoclonal détectant TLR9 dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour TLR9 anticorps (AA 26-193) (ABIN7193346)

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR9 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 5B10E8

Détail du produit anti-TLR9 anticorps

Épitope: AA 26-193

Fonction: CD289 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD289 (AA: 26-193) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TLR9

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Autre désignation: CD289

Sujet:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Poids moléculaire: 116 kDa

UniProt: Q9NR96

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades