IDH2 anticorps (AA 1-143)

N° du produit ABIN7193379

Cet anticorps anti-IDH2 est un anticorps Souris Monoclonal détectant IDH2 dans IHC, ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour IDH2 anticorps (AA 1-143) (ABIN7193379)

Antigène: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDH2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 3E8E9

Détail du produit anti-IDH2 anticorps

Épitope: AA 1-143

Fonction: IDH2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human IDH2 (AA: 1-143) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur IDH2

Antigène: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Autre désignation: IDH2

Sujet:

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Poids moléculaire: 50.9 kDa

ID gène: 3418

UniProt: P48735

Pathways: L'effet Warburg