KDM2A anticorps (AA 1-150)

N° du produit ABIN7193407

Cet anticorps Souris Monoclonal détecte spécifiquement KDM2A dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour KDM2A anticorps (AA 1-150) (ABIN7193407)

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KDM2A est non-conjugé

Application: ELISA

Clone: 5C11F7

Détail du produit anti-KDM2A anticorps

Épitope: AA 1-150

Fonction: KDM2A Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur KDM2A

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Autre désignation: KDM2A

Sujet:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Poids moléculaire: 132.8 kDa

ID gène: 22992

UniProt: Q9Y2K7

Pathways: L'effet Warburg