PRNP anticorps (AA 23-230)

N° du produit ABIN7193415

Cet anticorps anti-PRNP est un anticorps Souris Monoclonal détectant PRNP dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour PRNP anticorps (AA 23-230) (ABIN7193415)

Antigène: PRNP (Prion Protein (PRNP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRNP est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 3G10G9

Détail du produit anti-PRNP anticorps

Épitope: AA 23-230

Fonction: CD230 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD230 (AA: 23-230) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PRNP

Antigène: PRNP (Prion Protein (PRNP))

Autre désignation: CD230

Sujet:

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Poids moléculaire: 27.7 kDa

ID gène: 5621

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation