GANP anticorps (AA 293-442)

N° du produit ABIN7193448

Détail du produit anti-GANP anticorps

Antigène: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Épitope: AA 293-442

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GANP est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human MCM3AP (AA: 293-442) expressed in E. coli.

Clone: 5B2C4

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur GANP

Antigène: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Autre désignation: MCM3AP (MCM3AP Produits)

Synonymes: anticorps GANP, anticorps MAP80, anticorps SAC3, anticorps mKIAA0572, anticorps minichromosome maintenance complex component 3 associated protein, anticorps germinal-center associated nuclear protein, anticorps Mcm3ap, anticorps MCM3AP, anticorps mcm3ap, anticorps LOC100026233

Sujet:

Description: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.

Aliases: GANP, SAC3, MAP80, PNRIID

Poids moléculaire: 218.4 kDa

ID gène: 8888

Pathways: Protein targeting to Nucleus