TLR1 anticorps (AA 172-425)

N° du produit ABIN7193807

L’anticorps Souris Monoclonal anti-TLR1 a été validé pour IHC, ELISA, FACS et ICC. Il convient pour détecter TLR1 dans des échantillons de Humain.

Aperçu rapide pour TLR1 anticorps (AA 172-425) (ABIN7193807)

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3B1D8

Détail du produit anti-TLR1 anticorps

Épitope: AA 172-425

Fonction: CD281 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD281 (AA: 172-425) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TLR1

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Autre désignation: CD281

Sujet:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Poids moléculaire: 90.2 kDa

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades