TRIB2 anticorps (AA 1-200)
Aperçu rapide pour TRIB2 anticorps (AA 1-200) (ABIN7193902)
Antigène
Voir toutes TRIB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-200
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Fonction
- TRIB2 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human TRIB2 (AA: 1-200) expressed in E. Coli.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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Autre désignation
- TRIB2
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Sujet
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This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
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Poids moléculaire
- 38.8 kDa
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ID gène
- 28951
Antigène
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