TSG101 anticorps (AA 167-374)

N° du produit ABIN7193932

Cet anticorps Souris Monoclonal détecte spécifiquement TSG101 dans IHC, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour TSG101 anticorps (AA 167-374) (ABIN7193932)

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 8E10D10

Détail du produit anti-TSG101 anticorps

Épitope: AA 167-374

Fonction: TSG101 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101

Sujet:

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Poids moléculaire: 44 kDa

ID gène: 7251

UniProt: Q99816