TIMD4 anticorps (AA 75-170)

N° du produit ABIN715631

L’anticorps Lapin Polyclonal anti-TIMD4 a été validé pour ELISA, WB, IHC (p), IHC (fro), IF (p) et IF (cc). Il convient pour détecter TIMD4 dans des échantillons de Humain.

Aperçu rapide pour TIMD4 anticorps (AA 75-170) (ABIN715631)

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMD4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-TIMD4 anticorps

Épitope: AA 75-170

Homologie: Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TIM4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TIMD4

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Autre désignation: Tim4

Sujet:

Synonyms: SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T cell immunoglobulin and mucin domain containing protein 4, T-cell immunoglobulin and mucin domain containing 4, T-cell membrane protein 4, TIM-4, Tim4, Tim 4, TIMD 4.

Background: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

ID gène: 91937

Pathways: Cancer Immune Checkpoints